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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde06b23227f408e4014e36e5453a203a1997f322cb5901ba2a355e131e210b5' 
  AND token = 'AkuCZG/lyq7TVIZlYtxBcE5zyIEVQigOHNGNbFdTFyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}