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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be8ff049612c586e737286fc4c91625d9565f787b66697a649c0d97f9fe5c58b' 
  AND token = 'GVMdojeIrNQ5orRTFkOtIRQPzgKExppHCq1CeBz5GaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}