SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bdb32586864d70f931ddb2907d7f62d03dee3e52ad880db56d80b0e21e6f42' 
  AND token = 'l0j7TG4CbtrpTGVTpnqK1HzzRYPAehDhd9iuc1VZ77g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}