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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99414c06e8891f18d5094e39c715a89a0811394db71983c79437be071ccdd6fd' 
  AND token = '/xQ5hi2tL6k3Ao8Xz/2tLMX2OJ422+qx3+m8oYSxjyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}