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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61b363224eb498589d90b4c3aaa0662b46f2fad8a6ab6330f11d3920f82684c2' 
  AND token = 'KRMnxF55NxYtbt/rH+jdi++/RujRMBWbyZMFaYOAAsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}