SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24425dd8f8dba9f46eb66a7da73c4ab145f5aaedba644fcd914604c37c0f6057' 
  AND token = 'Qpq+t884Es6eO6OiefgwswkISXbvmM1/Z2nAmRn1GeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}