SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49d359f8a743c75f427601b28331753bdb64142e9c4a5ac9aba2f1263146b56' 
  AND token = 'BEL55131OrC0kSP3OhbcgBYoJj3o3TRO5k8NV1B0Qgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}