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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '326e1906b9f491e3b0b260c5eb7fd96d0990208cd8a2e5b4048ebcde9680b257' 
  AND token = 'zafygNjZTCNfB2NXms/+d6kzDpSP6OiJG+MT8tMikzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}