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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654a9f106d782333e64c0a9304170e9ecf5a91266524a0d4c416d5e663bc7c2f' 
  AND token = 'D2IO0+o9QbHTPg1h2QTToVaKeZLgPVio0buiinzksOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}