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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26fa6bdb67758f27e6fe9605a3b8dd81b5d5d5b352e3346463ee9460240920e3' 
  AND token = 'FPlWMDhIi0mQxcrSsZwR7VW22vPAxB3xOP3CRZES8Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}