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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6accfc9372dbc0d7dcd1925a4dbd4579683fd45da6a347cd9e2c9bdcc7297d7e' 
  AND token = 'SDXIbtkNa3BDxlVyCqO2lacw22VFChV/3Sf1JP8hds8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}