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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5a75020f2d75fcf2e80b39bf1217b427987101367a40c32b4016606b279ea0' 
  AND token = 'oe/kTgzR+Qfe6JYWmMVysQOktS9pdfioe291mwhW8fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}