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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01d4c6c1741d3bb0b20285bd04e715e5a42b66a85c98c7213a59e1248b90731e' 
  AND token = 'eMJSTs7Oo0wcPstKIzLguTKixtyyoqWm2UnlXKBlw58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}