SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49893d72a147cbd6b7d22a2f655963e99cf7957020c392f679203851e5eaa5ef' 
  AND token = '9p8U3vVYe08Q+DctZKhq7xFTdCvgeo1OJU6GoU47Sk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}