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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a189ca18a2fc993f61fb67c22b891ab8f37540c92eb18223ec0501b02ca6b78' 
  AND token = 'PAnhOs9XeEB5p+Gl37/7SNFP7Rh6phpeTN4Js1a2YY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}