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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1dadd4dd4c590b6648506fdacc539e372b4e0168e737ca98022459e84e91ec' 
  AND token = 'kRe8msNKDQSFFFmG/NAoylgeV7sgftWCcLCMWgoxBTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}