SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b059e74ad780efdbbdb08b632a2527c69fc715776b116cf56e0c3f5b4acd8ada' 
  AND token = 'B5w4g7LgKRBA/pqtjUt/kq4HcVWqJcj9gxSzHHbAZEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}