SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '501bd23e2fd2f361ad31807bdfe6d09a56775c414f63642ad861ae1bc850fa0e' 
  AND token = 'fc/lvK/uezYvEKzMkWfHaR0lx7PpybeL9V5mye3usjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}