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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a48099741aaa836870e239c03d2a45554e8dd9d2b25f59df96d05119e70821' 
  AND token = 'u+P1Ei1im78TGQzkMF+EQN+DD0TWHARXqK1H9ytZ+FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}