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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac2ba9a7e423a599da56fe5160c3d64e2a0876e23992ff339bbbecaf61657370' 
  AND token = 'RBbFyZhkMGkbLSi6vxSknO2Kj6m0exJ50hFZI88X5Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}