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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3cd1455fcb661a7677d0037832faae10b4130f7f9107c868326c576576173e6' 
  AND token = '7qBf3QVj1PVoGKqbe+7PeMg2GPC4IANAkzBvd2Mfwt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}