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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cddc9b66645e21ec0752b7e06a668099e6245c6e27944edbbda53598ea0da7a' 
  AND token = 'yV2o/V0QpABM06Xy22L/PJg7mA+IUWBngyHoIncdu1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}