SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8bf42fd5d23f78d02d41005792bbb15b61f8b5ec072df15bd5f750a09301cc6' 
  AND token = 'VX12VtCLxXOM2EX3tP5gq8ILwLI0BJXDmTL7CoozeqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}