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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a63dd25ea7ad711a423d3c2a702301baa009069e5a41015e0823ee5d10c15b0' 
  AND token = 'wFQvn3fAZ/tg5sn7/hULY1uXJhBFFa1z2XMTEV8D0RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}