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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a32fa4df2a062eecda704af859f9428f7909542f9fff21f766edca7d94b1f76' 
  AND token = 'EyItqDcoUAVLLWzhYMJO5M59NNxDGXBAeKJiXGRAbKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}