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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a05a3ad7a4f38afd8e3719054b3f5ea82d71c37caafc54774ccec5a1f5ef7c' 
  AND token = '5hadKqtqpw0SwOCH/xRraTfdIXQ7YvMUt4ZAImn3n+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}