SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21716e282fc6bef0ed727de46806655b0ebf8fdc7c2dd635bd3531f5fe77c60' 
  AND token = 'j/y+gItKaiWMAsZFkNZBxRyU5v+phpO7XAS6mZ8bxQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}