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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '271cb5e7b84e096935a2a0c1dc85b23465cb6fb9c363b85ab37b4fb86cd647fc' 
  AND token = 'AaziElu6rT1vg/Qr0zTQ2ZgbNbGKETQc6mPyruUd7NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}