SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd497f53cc5bae4f2568d5b3d438a7a8ca3578c31c9cacee1788e0c384f05b3dd' 
  AND token = 'sbRAZ6GmoyltKI7/DnyFPb4y4VhIqZftBD9WHv2Nf3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}