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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2625bff548ffe6055651b990aec9fe58ce5d7d8a3281f4b06d03e4dc4a39a57d' 
  AND token = 'W2f9usNtFJmzzuMfwikdVe7CyWSfHTiR3FLiz+i+pGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}