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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33273797d42c5930b2f459f5ed8c90aca75f6a06f2a442e1f812c2c17f8151e1' 
  AND token = 'Mvl9IW0F0IMTk3FCbZ7HpPfsNmb85TQkuxD6AE5E6xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}