SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '809e8b3462d267eae94183f6f1d06c1ffdf29b8286e1d4679c168381a8bccfc5' 
  AND token = 'i/V0eEDZNkOGzTj7fK+nRbwLJVJweXM1lxzfue51zXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}