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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '948fb9065828463f48f81859863afb6a41f78f98044939fa95f413f325381467' 
  AND token = 'KvavPbcZukD6l64OlvNFErreNrmsLIg5GOzbpaKpzwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}