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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72373e3b8631e1ba3f7a3b76e74ee2462deab1af10e8b0b281044348de79fb51' 
  AND token = 'o0FX/rI4nlV3lrmLc5ubAbXgP/SyCiefDMXO9sx5Da4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}