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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5009eacf1eb8ccaacae782eecb0e9e14cfadb08b31ca9b53ea36c154fd651528' 
  AND token = 'N6RbgtKRk/DJ6C+lMU7o8Yx/8B/cSsYwQ0mc42zdl30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}