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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456f298a31ac6e7c483c6070042f968af1553738391e876469d0e55fc85e0118' 
  AND token = 'PrqoyZfeFVRXmXX3v8L75hk6InFN/pwDtl6rcxoWtqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}