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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf4a4d5855064f157a4552f94158748c89ba0995439cfdad9e40dddc68ac734f' 
  AND token = '612jxMAB7ogH0qPg1OjW+LWIiHWzIncjfo+X3Lm+8PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}