SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69d36627edc2e2aa75030eeaeb42e796aa63e8777ae36fafd1c173f22e000618' 
  AND token = 'UwFr01YsFI/Yc3ZLKsdSmF5HsE58RxP6u0jGbLki2R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}