SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28dea4135b1b879b4d24f644c46d6d31f4435b37fb5b74c26f0ee661c2e1087' 
  AND token = '11zoF5YA2QekzSrlya8HFuvQRx1CHYiEm7gEGhBxYbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}