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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3adbc9e10dd38401fa5ee6724e3d729a9cb26aea4825e8948987e37cb5df1f9c' 
  AND token = '49jd+yYRZVrqDLJiiCKov9rBXpdFPaVikkA8po2ZJak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}