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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03eb8c947606508f271355bb1f74d24a216a6716b300c5d0138320f66687684a' 
  AND token = 'NUsho8YYN8mLF6obqNI+6X46GcvPP7I7qZOeUeCNQV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}