SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a2ac46644b8945edb829d61347d3f100fb0d95211f3c8b71911ed6f8542345' 
  AND token = 'KvbnDerAcxtZDAlinX2DeI6ep/S0X20ijU7l2OLH+fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}