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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23f850c0c8b4f0cab9146591c1ded54a8e17a290f8df040aac7aec384c2616a1' 
  AND token = 'V9ISxwcM5rLjF0tUDEezsYjZWmlB5yMmOAf+AwCx7xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}