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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c8442e77bddcf86bffea273fb343934b750b1e97678ea0734ef0a6dff0656fa' 
  AND token = 'eXD3J71fVZHByQL8nnSvOn5DAv6E+3c+yrAs7twLaos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}