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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c131d08e1c57bb87e71c15c8eb97f4d77c562bd2feb9fa513ad045bd0bcffd03' 
  AND token = 'HBe1YbTnH6Sqe9pkEnziDb5vOmBxrOsJmgiGGTvB9Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}