SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2d3621d4d584b1a59a357113f6dcea596ebd2b1657a371fcadc55012f196fd' 
  AND token = 'nKk4qaJ7DD4RA3kQsEJmgGFS40/chXzvBh0nMBsZefw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}