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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '941a59ba8c212ed53829d1e2085bf051249f7ca5285a2fb7581e21f266662875' 
  AND token = 'MZI+tZSJjC5Z16/EQ1K0KnwzeAJK2jT/0oSnQi0rnE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}