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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdede33d4abafe2b1a521efb381885f1ed00a1586d11b57a0ff3e0b236888ce1' 
  AND token = 'MsUTBF1/T3mbGXiMCpVOi1JAcyQ+3NKElMdZqrdB8ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}