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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d3124bd864f77406550f5bd8548f4831dc2d348bf006a2042759a144efbfa3' 
  AND token = 'H9c+2WQ7OoDvqzbAI4s0O5cK2Ft+mY8y3yJOVchpguY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}