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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddbf1a0534b1a286758d00a4cf511f53d362d3bc17014501cd47185cc9a7c1b9' 
  AND token = 'nPvX23KGgZhm5dEaQtbk8vpXA94LOt1AV0RYCyjjG1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}